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. 2017 Apr 19;13(4):e1006352. doi: 10.1371/journal.ppat.1006352

Fig 7. Inhibition of infection in cells depleted of β6 and β8 integrins.

Fig 7

(A) Extent of integrins silencing. SK-OV-3 cells were doubly silenced for β6 and β8 integrins (siRNA β6+β8), or mock-silenced (siRNA ctrl). Extent of silencing was measured by qRT-PCR, and expressed as fold decrease relative to siRNA ctrl cells. Each column represents the average of triplicates from two independent experiments ± S.D. (B) Effect of integrins silencing on infection. SK-OV-3 cells silenced with siRNA ctrl, or siRNA β6+β8, were infected with wt R-LM5, R-LM113, R-LM249, R-809 and R-909 (5 PFU/cell), and harvested 24 h later. The extent of infection was quantified by flow cytometry. Each point represents the average of triplicates. Bars show S.D.