| Hormone signaling |
| Inhibition of the PS-IAA4/5-GUS reporter in the presence of naphthaleneacetic acid |
Yokonolide A, yokonolide B, terfestatin A, compounds A to C, 2-furylacrylic acid |
Inhibitors of auxin signaling/not identified |
– |
Hayashi et al. (2001, 2003); Armstrong et al. (2004); Yamazoe et al. (2005); Sungur et al. (2007)
|
| Activation of the pUGT74E2:LUC reporter |
2-Furylacrylic acid |
Inhibitor of auxin signaling and mitochondrial function/not identified |
– |
Kerchev et al. (2014) |
| Inhibition of root elongation |
WH1 to WH13 |
Activators of auxin signaling/auxins |
– |
Christian et al. (2008) |
| Inhibition of growth |
2-[4-(Diethylamino)-2-hydroxybenzoyl]benzoic acid |
Inhibitor of auxin signaling/ABCB19 |
Candidate approach |
Kim et al. (2010) |
| Aberrant root development |
Rootin |
Modifier of the PIN-mediated auxin distribution/not identified |
– |
Jeong et al. (2015) |
| Inhibition of the gravitropic curvature of maize coleoptiles |
Yucasin |
Inhibitor of IAA biosynthesis/YUC |
Candidate approach |
Nishimura et al. (2012, 2014)
|
| Inhibition of gravitropism and localization of the GFP:δ-TIP |
Gravacin |
Auxin transport inhibitor/PGP19 |
Compound-resistant screen |
Surpin et al. (2005); Rojas-Pierce et al. (2007)
|
| Promotion of hypocotyl elongation in det2-1 mutant/modifiers of acl5 mutant/rescue of the cat2 mutant |
Proauxins |
Activators of auxin signaling/proauxins |
– |
Savaldi-Goldstein et al. (2008); Yoshimoto et al. (2012); Kerchev et al. (2015)
|
| Activation of the CYCB-GUS reporter in xylem pole pericycle cells |
Naxillin |
Promotion of IBA-to-IAA conversion/not identified |
Compound- resistant screen |
De Rybel et al. (2012) |
| Inhibition of the constitutive ethylene response phenotypes eto1-2 and ctr1-1
|
l-Kynurenine |
Inhibitor of the indole-3-pyruvic acid pathway of auxin biosynthesis/TAA1, TARs |
Candidate approach |
He et al. (2011) |
| Inhibition of the ethylene response in etiolated eto1-4 seedlings |
Acsinones (9370, 9393, and 73033) |
Inhibitors of ethylene biosynthesis/ACC |
Candidate approach and compound- resistant screen |
Lin et al. (2010); Chen et al. (2013)
|
| Inhibition of hypocotyl elongation in dark |
Brassinopride |
Inhibitor of brassinosteroid biosynthesis/not identified |
– |
Gendron et al. (2008) |
| Promotion of hypocotyl elongation in light |
Bikinin |
Activating brassinosteroid signaling/BIN2 |
Candidate approach |
De Rybel et al. (2009) |
| Repressors of LOX2p < LUC expression |
Jarin-1 |
Inhibitor of jasmonate responses/JAR1 |
Candidate approach |
Meesters et al. (2014) |
| Inhibition of cotyledon expansion and greening after germination |
Cotylimides |
Inhibitors of strigolactone biosynthesis/not identified |
– |
Tsuchiya et al. (2010) |
| Suppression of hypocotyl inhibition by GR24 in light |
Soporidine |
Inhibition of strigolactone signaling/HTL, KAI2 |
Candidate approach |
Holbrook-Smith et al. (2016) |
| Inhibition of seed germination and hypocotyl growth in dark |
Hypostatin/Glc-hypostatin |
Inhibition of cell expansion/not identified |
Compound-resistant screen |
Zhao et al. (2007) |
| Inhibition of seed germination and hypocotyl growth in dark |
Pyrabactin |
Selective ABA agonist/PYR, PYLs |
Compound-resistant screen |
Zhao et al. (2007); Park et al. (2009)
|
| Inhibition of seed germination |
Germostatin |
Activator of auxin signaling/not identified |
Compound-resistant screen |
Ye et al. (2016) |
| Cell wall homeostasis |
| Organ swelling |
Morlin |
Altered movement of CESA/not identified |
– |
DeBolt et al. (2007) |
| Cell swelling in tobacco suspensions expressing GFP-α-tubulin |
SS compounds, cobtorin, lasalocid sodium |
Altered cell wall properties through affecting microtubule dynamic and enzymatic saccharification/not identified |
Compound-resistant screen |
Yoneda et al. (2007, 2010); Okubo-Kurihara et al. (2016)
|
| Induction of polyploidy in H2B-YFP-expressing cells |
C17 |
Inhibition of cellulose biosynthesis/not identified |
Compound-resistant screen |
Hu et al. (2016) |
| Inhibition of pollen germination and growth |
Cestrin |
Altered movement of CESA/not identified |
– |
Drakakaki et al. (2011); Worden et al. (2015)
|
| Inhibitors of lignin deposition |
39 compounds, p-iodobenzoic acid |
Inhibitor of the phenylpropanoid pathway/Cinnamate 4-hydroxylase |
Candidate approach |
Van de Wouwer et al. (2016) |
| Endomembrane trafficking |
| Inhibition of pollen germination and pollen tube growth/effectors of the circadian clock |
ES1/(Prieurianin) |
Actin cytoskeleton inhibitor/not identified |
– |
Robert et al. (2008); Tóth et al. (2012)
|
| Inhibition of pollen germination and pollen tube growth |
ES2 |
Exocytosis inhibitor/EXO70 |
Affinity pull down |
Drakakaki et al. (2011); Zhang et al. (2016)
|
| Inhibition of pollen germination and pollen tube growth |
ES3, ES5 |
Trafficking modifiers/not identified |
– |
Drakakaki et al. (2011) |
| Inhibition of pollen germination and pollen tube growth |
ES7 |
Late cytokinesis inhibitor/not identified |
– |
Drakakaki et al. (2011); Park et al. (2014)
|
| Inhibition of pollen germination and pollen tube growth |
ES8 |
Basal polarity effector/not identified |
– |
Drakakaki et al. (2011); Doyle et al. (2015)
|
| Inhibition of pollen germination and pollen tube growth |
ES9 |
Endocytosis inhibitor/protonophore |
Candidate approach |
Drakakaki et al. (2011); Dejonghe et al. (2016)
|
| Inhibition of pollen germination and pollen tube growth |
ES16 |
Apical polarity effector/RabA |
Candidate approach |
Drakakaki et al. (2011); Li et al., (2017)
|
| Inhibition of pollen germination and pollen tube growth |
C834 |
Vacuolar trafficking inhibitor/not identified |
– |
Drakakaki et al. (2011); Rivera-Serrano et al. (2012)
|
| Inhibition of pollen germination and pollen tube growth |
22 compounds |
Inhibitory or stimulatory effects in pollen tube and root growth assays/not identified |
– |
Chuprov-Netochin et al. (2016) |
| Affected gravitropism and localization of the GFP:δ-TIP |
TE1 |
Trafficking modifier/not identified |
– |
Surpin et al. (2005); Paudyal et al. (2014)
|
| Affected gravitropism and localization of the GFP:δ-TIP |
LDS-003655 |
PTS1 and PTS2 peroxisome matrix import pathways/not identified/ |
– |
Surpin et al. (2005); Brown et al. (2011)
|
| Immunity and cell death |
| Modifiers of elicitor-responsive gene expression |
Oxytriazine, fluazinam, cantharidin, enpiclonil |
Pathogen-associated molecular pattern-triggered innate immune responses/not identified |
– |
Serrano et al. (2007) |
| Modifiers of elicitor-responsive gene expression |
Triclosan |
Pathogen-associated molecular pattern-triggered innate immune responses/MOD1 |
Candidate approach |
Serrano et al. (2007) |
| Suppressors of AvrRPM1-RPM1-dependent cell death |
4,15-Diacetoxyscirpenol, neosolaniol |
Inhibition of AvrRpm1 synthesis/not identified |
– |
Serrano et al. (2010) |
| Enhanced Pst-avrRpm1-induced cell death |
Imprimatin A and B |
Salicylic acid metabolism/UGT74F1 and UGT76B1 |
Candidate approach |
Noutoshi et al. (2012b) |
| Activation of the pathogen-responsive reporter CaBP22p::GUS
|
3,5-Dichloroanthranilic acid, 2-(5-bromo-2-hydroxy-phenyl)-thiazolidine-4-carboxylic acid |
Activation of plant defense signaling/not identified |
– |
Knoth et al. (2009); Rodriguez-Salus et al. (2016)
|
| Resistance to Pseudomonas syringae/enhanced Pst-avrRpm1-induced cell death |
Sulfonamides |
Not determined/not identified |
– |
Schreiber et al. (2008); Noutoshi et al. (2012a)
|
| Suppression of the ABA-induced RAB18 reporter |
[5-(3,4-Dichlorophenyl) furan-2-yl]-piperidine-1-ylmethanethione (DFPM) |
Activation of plant immunity via Ca2+ signaling/not identified |
– |
Kim et al. (2011, 2012); Kunz et al. (2016)
|
| Suppression of CYCLIC NUCLEOTIDE-GATED ION CHANNEL11 (AtCNGC11) and AtCNGC12 gain-of-function mutant cpr22-induced lethality |
Diethylstilbestrol, erythrosin B, dibucaine |
Ca2+ channel inhibition/not identified |
– |
Abdel-Hamid et al. (2011) |
| Plant development |
| Vein pattern effectors |
PATI-1 to PATI-4 |
PATI-1 and PATI-2 inhibitors of PIN2 cycling/not identified |
– |
Carland et al. (2016) |
| Vein pattern effectors |
HYVP-1 to HYVP-3 |
Agonists of auxin transport/not identified |
– |
Carland et al. (2016) |
| Vein pattern effectors |
OVP-1 and OVP-2 |
OVP-1 targets BR signaling/not identified |
– |
Carland et al. (2016) |
| |
|
OVP-2 targets MAPKKK signaling/not identified |
– |
|
| Rescue or mimic the amp1 phenotypes |
Hyperphyllin |
AMP1 regulatory pathway/not identified |
– |
Poretska et al.. (2016) |
| Stomatal patterning effectors |
Bubblin |
Inhibits stomatal asymmetric division/not identified |
– |
Sakai et al., (2017) |
