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. 2017 May 1;4(2):ENEURO.0352-16.2017. doi: 10.1523/ENEURO.0352-16.2017

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Copyright © 2017 Walton et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 2. — Rhythmic GABA_AR mRNA expression in the SCN. Expression of the extrasynaptic GABA_Aδ receptor mRNA (A, D) varied by circadian phase in a 14:10 LD cycle (A) with the highest level of expression during the day. Expression of the synaptic GABA_Aγ2 receptor RNA did not significantly vary across the day (B, E). The ratio of extrasynaptic-to-synaptic receptor mRNA (δ:γ2) (C, F) varied by circadian phase after 10 d in DD conditions (F), with the highest relative expression of GABA_Aδ occurring during the inactive phase (subjective day). *p ≤ 0.05. Statistics in Table 2.