Table 1.

Variation of cone photoreceptor density analyzed by three different methods for healthy subjects

Methods	0.5 mm	1.0 mm	1.5 mm
RSM	28,436±2,426***	21,233±1,796	13,620±1,348
SFM	29,727±2,474	20,777±1,767	13,764±1,233*
MIM	29,894±2,043	21,020±1,583	13,481±1,156

Notes: Average cone density of 150 trials (10 sequential trials of 15 healthy subjects, cells/mm²) ± SD.

^*P<0.05 (SFM > MIM, Wilcoxon rank sum test) and

^***P<0.001 (RSM < MIM, Wilcoxon rank sum test).

Abbreviations: RSM, region-based segmentation method; SFM, spatial filtering method; MIM, manual identification method; SD, standard deviation.