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Schematic diagram of the nuclear ribosomal repeat unit in fungi. This region includes the 18S, 5.8S and 28S rRNA genes and the internal transcribed spacers (ITS) 1 and 2. Sites of universal primers used by molecular surveys of the oral mycobiome and by one landmark skin mycobiome study are indicated by arrows. As seen in the Figure, studies commonly rely on ITS1 amplification.
