Fig. 7.

Representative photomicrographs of an advanced coronary lesion (female, 19 months old). Panels A–L are serial sections. Panel D is a higher magnified view of the square area in panel C. Arrows in panel B indicate calcium accumulation. In panel D, arrows indicate the vasa vasorum, and arrowheads indicate the internal elastic lamina. In panels E–H, arrows indicate positive cells for MMPs and DLH3. IgG2a, IgG1, IgG2b, and IgM were used instead of MMP-1, MMP-9, MMP-12, and DLH3, respectively, for negative control staining.