Table 1.
Clinical diagnosis | Number of cases* | Mean age [±SD] at time of biopsy | Gender ratio [M:F] | |
---|---|---|---|---|
Secondary lymphoid tissue | Reactive tonsil | 5 | not available** | not available** |
BIDs | Atopic dermatitis | 10 | 56 [±16] | 6:4 |
Contact dermatitis | 11 | 52 [±17] | 8:3 | |
Pityriasis rosea | 8 | 38 [±14] | 4:4 | |
Psoriasis vulgaris | 8 | 51 [±23] | 5:3 | |
Lichen planus | 10 | 62 [±16] | 4:6 | |
CTCL | MF patch/plaque | 11 | 63 [±12] | 9:9 |
MF tumor | 4 | |||
SS skin | 3 | |||
CTCL cell lines | MyLaa | 5 | n/a*** | 3:2 |
SeAxb | ||||
Hut78b | ||||
SZ4b | ||||
HHc |
One biopsy per patient was assessed in 64 cases. Two biopsies corresponding to two different lesion types (plaque and tumor) were evaluated in one patient with tumor-stage MF.
Tonsil tissue from 5 distinct individuals was obtained as de-identified specimens. Human CTCL cell lines were originally derived from an MF plaque b and from the peripheral blood of patients with SS c or with an unspecified leukemic-stage CTCL d.
Mean age [±SD] of patients at time of cell harvest: 66 [±11].
BIDs: benign inflammatory dermatoses; CTCL: cutaneous T-cell lymphoma; MF: mycosis fungoides; SS: Sézary syndrome.