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. 2017 Feb 2;5(1):16–22. doi: 10.14218/JCTH.2016.00052

Table 2. Health outcomes by patient subpopulation (per 10,000 patients).

Cases of: Treatment naïve non-cirrhotic Treatment naïve cirrhotic Treatment experienced non-cirrhotic Treatment experienced cirrhotic
2nd Gen DAA 1st Gen DAA + not treated 2nd Gen DAA 1st Gen DAA + not treated 2nd Gen DAA 1st Gen DAA + not treated 2nd Gen DAA 1st Gen DAA + not treated
Hepatic decompensation - 1,990.8 1,533.9 3,883.7 326.9 2,211.4 1,444.0 4,143.4
Hepatocellular carcinoma 23.7 1,493.3 1,397.7 2,771.4 264.6 1,656.2 1,345.2 2,923.2
Liver transplantation - 273.9 229.4 592.5 44.2 304.2 215.8 632.6
Liver-related death 20.5 2,718.6 2,417.4 5,506.9 456.4 3,017.4 2,302.3 5,847.9
Life years 19.5 17.9 17.3 14.6 19.2 17.7 17.4 14.3
Quality adjusted life years 16.2 14.1 13.8 11.0 16.0 13.9 13.9 10.6

1st Gen DAA, first generation direct-acting antiviral agents; 2nd Gen DAA, second generation direct-acting antiviral agents. Analysis only includes patients with hepatitis C genotype 1. Results are presented per 10,000 patients.