FIG 2.

Epitope mapping of RSV G-specific antibodies. (A) An SPR array of 12-aa peptides that were partially overlapping was used to determine the binding epitope of G-specific antibodies. The lines depict the binding response (in relative units [RU]; 1 RU is 0.1 millidegrees) to the corresponding peptide numbers. Three linear epitopes can be distinguished: epitope B (131-2G, AT34, AT40, AT64G), epitope C (AT50, AT51, AT61G), and epitope D (AT32, AT33). (B) Amino acid sequence of the RSV-A2 G protein, indicating the binding epitope of each antibody.