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Complement-dependent and -independent RSV neutralization by G-specific antibodies. RSV-A2 or RSV-B on HEp-2 cells was neutralized in vitro by increasing the concentration of antibodies specific for the RSV G protein with 10% rabbit complement (A and B) and without complement (C and D). AT12-009, an HCV E2-specific antibody, was used as a negative control. AM22 is a prefusion F protein-specific antibody. All experiments were performed twice in triplicate.
