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. 2017 Apr 1;7(4):770–783.

Figure 5.

Figure 5

The effects of lncRNA-ATB on miR-200s, ZEB1, and ZEB2. A. MiR-200s expression levels in lncRNA-ATB stably overexpressed and control MG63 cells. B. MiR-200s expression levels in lncRNA-ATB stably depleted and control U2OS cells. C. Luciferase activity in lncRNA-ATB stably overexpressed and control MG63 cells co-transfected with miR-200s mimics and luciferase reporters containing ZEB1 3’UTR, ZEB2 3’UTR, or nothing. D. Luciferase activity in lncRNA-ATB stably depleted and control U2OS cells co-transfected with miR-200s inhibitors and luciferase reporters containing ZEB1 3’UTR, ZEB2 3’UTR, or nothing. E. ZEB1 and ZEB2 mRNA levels in lncRNA-ATB stably overexpressed and control MG63 cells transfected with miR-200s mimics. F. ZEB1 and ZEB2 protein levels in lncRNA-ATB stably overexpressed and control MG63 cells transfected with miR-200s mimics. G. ZEB1 and ZEB2 mRNA levels in lncRNA-ATB stably depleted and control U2OS cells transfected with miR-200s inhibitors. H. ZEB1 and ZEB2 protein levels in lncRNA-ATB stably depleted and control U2OS cells transfected with miR-200s inhibitors. Results are present as mean ± SD. *P<0.05, **P<0.01, ***P<0.001 by Student’s t-test.