Figure 6.

p62/SQSTM1 excess can predict radiotherapy resistance in hypopharyngeal carcinoma cases. A. In 32 cases of hypopharyngeal carcinomas treated primarily with radiation, excessive p62+ cases (high p62/SQSTM1 levels) showed significantly worse prognosis than p62- cases. B. There was no significant difference for the prognosis between p62+ and -cases treated primarily with surgical procedure. The association between p62/SQSTM1 excess and clinical DFS was evaluated statistically using the Kaplan-Meier curve together with log-rank test.