Table 1.
Relationship between p62 and clinicopathological parameters in 54 hypopharyngeal carcinomas
| p62/SQSTM1 | ||||
|---|---|---|---|---|
|
|
||||
| Parameters | No. of cases | Negative | Positive | p-values |
| Age at diagnosis | ||||
| ≤ 65 years | 27 | 8 | 19 | 0.7613 |
| > 65 years | 27 | 7 | 20 | |
| Gender | ||||
| Male | 47 | 14 | 33 | 0.6586 |
| Female | 7 | 1 | 6 | |
| Stage: TNM class | ||||
| ≤ II | 10 | 4 | 6 | 0.4376 |
| ≥ III | 44 | 11 | 33 | |
| T classification | ||||
| ≤ T2 | 24 | 7 | 17 | 0.8385 |
| ≥ T3 | 30 | 8 | 22 | |
| Nodes status | ||||
| Negative | 18 | 4 | 14 | 0.5192 |
| Positive | 36 | 11 | 25 | |
| Treatment | ||||
| Surgery: S | 22 | 6 | 16 | 0.9452 |
| Radiation: R | 32 | 9 | 23 | |
| Differentiation | ||||
| Well and moderately | 27 | 7 | 20 | 0.7613 |
| Poorly | 27 | 8 | 19 | |
| Ki67 | ||||
| ≤ 40% | 30 | 8 | 22 | 0.8385 |
| > 40% | 24 | 7 | 17 | |
| Nrf2 | ||||
| Negative | 25 | 10 | 15 | 0.0626 |
| Positive | 29 | 5 | 24 | |
Chi-square and Fisher’s exact tests were used to evaluate the relationship between clinicopathological parameters and p62 expression.