Table 2.
Univariate disease-free-survival analysis of clinicopathological data of 54 hypopharyngeal carcinomas
| Variables | Hazard ratio (95% confidence interval) | p-value | |
|---|---|---|---|
| Age at diagnosis (≤ 65 vs > 65) | 0.751 | (0.364-1.548) | 0.4385 |
| Gender (female vs male) | 1.009 | (0.351-2.899) | 0.9870 |
| TNM stage (≤ II vs ≥ III) | 0.983 | (0.375-2.584) | 0.9735 |
| T classification (≤ T2 vs ≥ T3) | 0.921 | (0.449-1.894) | 0.8242 |
| Nodes (negative vs positive) | 1.126 | (0.514-2.463) | 0.7674 |
| Differentiation (well or moderately vs poorly) | 1.241 | (0.602-2.558) | 0.5598 |
| Treatment (R vs S) | 0.543 | (0.248-1.189) | 0.1269 |
| Ki67 (≤ 40% vs > 40%) | 0.572 | (0.267-1.225) | 0.1508 |
| Nrf2 (negative vs positive) | 1.580 | (0.758-3.300) | 0.2222 |
| p62/SQSTM1 (negative vs positive) | 2.762 | (1.052-7.246) | 0.0392* |
The Cox proportional hazards regression model was used to evaluate the effects of clinicopathological parameters on disease-free-survival (DFS) with a 95% confidence interval (95% CI). DFS intervals were used as indicators for the relative hazards.
*
P < 0.05, statistically significant.