Table 2.
Anti-inflammatory effect of beta-sitosterol (BS); Determination of mieloperoxidase activity
| Treatment | Dose (mg/ear) | Inhibition % |
|---|---|---|
| TPA | 0.0025 | -- |
| IND | 0.5 | 95.36* |
| BS | 0.5 | 56.39* |
| BS | 1.0 | 79.20* |
| BS | 1.5 | 98.90* |
IND=indomethacin. The inhibiton percentage was calculated according to the equation %I=DAc-DAp x 100/DAc; where DAc is the arithmetic mean of the control absorbance, and DAp the arithmetic mean of the tested agent absorbance. The obtained results represent the mean ± EEM of 5 mice per group.
*
Statistically significant difference with respect to the value obtained in 12-O-tetradecanoylphorbol-13-acetate (TPA) treated animals; ANOVA and Student t tests, p≤0.05