Table 2.
Relationship between MTDH expression and clinicopathological variables of HCC from clinical samples in house
| Variables | Category | Total | N of positive Cases | Percentage | χ2 | P value |
|---|---|---|---|---|---|---|
| Gender | Female | 17 | 8 | 47.1 | 0.901 | 0.342 |
| Male | 72 | 43 | 59.7 | |||
| Age | <50 | 46 | 26 | 56.5 | 0.024 | 0.877 |
| ≥50 | 43 | 25 | 58.1 | |||
| Pathological grade | I-II | 19 | 7 | 36.8 | 4.134 | 0.042 |
| III-IV | 70 | 44 | 62.9 | |||
| Grade of differentiation | High | 6 | 2 | 33.3 | 1.906a | 0.386a |
| Median | 57 | 35 | 61.4 | |||
| Low | 26 | 14 | 53.8 | |||
| Liver cirrhosis | No | 46 | 27 | 58.7 | 0.075 | 0.784 |
| Yes | 43 | 24 | 55.8 | |||
| Tumor size (cm) | <5 | 15 | 11 | 73.3 | 1.895 | 0.169 |
| ≥5 | 74 | 40 | 54.1 | |||
| Distant metastasis | No | 43 | 19 | 44.2 | 5.851 | 0.016 |
| Yes | 46 | 32 | 69.6 | |||
| AFP | Negative | 54 | 31 | 57.4 | 0.026 | 0.872 |
| Positive | 35 | 20 | 57.1 | |||
| HCV | Negative | 60 | 34 | 56.7 | 0.031 | 0.861 |
| Positive | 29 | 17 | 58.6 | |||
| HBV | Negative | 16 | 13 | 81.3 | 81.3 | 0.032 |
| Positive | 73 | 38 | 52.1 |
Kruskal-Wallis H test was used to assess the correlation between MTDH expression and pathological grade.
The association between MTDH and other clinical variables were performed with χ2 tests.