Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Melatonin significantly increased SIRT1 signaling pathway. A and B. Melatonin increased the protein and mRNA levels of SIRT1. C and D. Melatonin increased the protein and mRNA levels of FoxO3a. E and F. Melatonin increased the protein and mRNA levels of Nrf2. G and H. Melatonin increased the protein and mRNA levels of Ho-1. Data were shown as mean ± SEM or as ratio. *P<0.05, **P<0.01, ***P<0.001.
