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. 2017 Apr 15;9(4):1783–1791.

Figure 4.

Figure 4

Effect of WP1130 on cell growth and apoptotic death in breast cancer cells. Breast cancer cell lines (MDA-MB-231, MDA-MB-468 and Bcap-37) were incubated with cisplatin alone or in combination with WP1130 for 48 h. Photomicrographs and bar charts depict the EdU staining and relative EdU-positive ratio, respectively, of (A) MDA-MB-231, (B) MDA-MB-468, and (C) Bcap-37 cells after treatment with cisplatin alone or in combination with WP1130 (2.5 µM). Symbols: * vs. control, P < 0.05; # vs. cisplatin, P < 0.05. (D) Flow cytometry was performed to detect the apoptosis rate of MDA-MB-231, MDA-MB-468, and Bcap-37 cells treated with cisplatin alone or combined with WP1130 (2.5 µM).