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. 2017 Apr 15;9(4):1845–1855.

Figure 3.

Figure 3

LncRNA XIST directly interacted with miR-137 in glioma cells. A. Bioinformatics tool (starBase2.0) revealed the predicted binding sites between XIST and miR-137. B and C. Luciferase reporter assay showed that miR-137 overexpression significantly decreased the luciferase activity of XIST-WT in glioma cells compared to controls, while miR-137 did not affect the luciferase activity of XIST-MUT. D. The expression of miR-137 in glioma cells transfected with XIST plasmid or siRNA were examined by qRT-PCR. E. Correlation analysis revealed the negative relationship between miR-137 and XIST in glioma tissues. *P<0.05.