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. 2017 Apr 15;9(4):1845–1855.

Figure 4.

Figure 4

LncRNA XIST up-regulated Rac1 by inhibiting miR-137 expression in glioma cells. The mRNA (A) and protein (B) levels of Rac1 in glioma cells transfected with miR-137 mimics, XIST plasmid or XIST siRNA were detected by qRT-PCR and western blot. (C and D) The relative luciferase activity of Rac1 3’UTR in glioma cells transfected with miR-137 mimics or miR-137 mimics + XIST plasmid. (E) Rac1 mRNA expression was significantly up-regulated in glioma tissues compared to normal brain tissues. (F) The correlation between XIST mRNA and Rac1 expression in 30 glioma tissues. *P<0.05.