Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 May 2;7:46428. doi: 10.1038/srep46428

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) Thermal stability of TPMTwt (black), TPMT p.Y240C (blue) and TPMT p.Y240S (green) in 10-fold (dashed line), 50-fold (solid line) molar excess of SAM or absence (dotted line) of SAM. Data from one representative measurement of each protein sample are shown in the graph. (b) Table showing thermal denaturation temperatures for TPMTwt, TPMT p.Y240C and TPMT p.Y240S. The thermal denaturation temperatures shown are determined by using the CDpal software⁴⁵ and merging all data points from each individual measurement. Data were fitted to the merged points using a two-state denaturation model.