Skip to main content
. 2017 Apr 26;9(4):320–331. doi: 10.4330/wjc.v9.i4.320

Figure 5.

Figure 5

Structure of Mypn gene and functional domain of the protein. The N-terminal domain containing two immunoglobulin (Ig) and coiled-coil domains binds to cardiac ankyrin repeat protein (Carp/Ankrd1), the negative regulator of muscle gene expression. The rod domain contains proline rich domain with phosphorylation residues and binds to the SH3-domain of nebulin/nebulette at the Z-discs. The C-terminal domain containing 3 Ig domains binds to α-actinin at the Z-discs.

HHS Vulnerability Disclosure