Table 4.
Genes whose gene expression has significant correlation with Mypn and gene product have significant change comparing with KI or KO mice
Protein code | Corr P value | KI/WT | KO/WT | KO/KI |
CGNL1 | 0.0024 | 1.58 | -1.03 | -1.63 |
PKP1 | 0.0082 | 1.76 | -1.13 | -1.99 |
SYNE11 | 0.0114 | -3.59 | 5.82 | 20.82 |
PYGB | 0.0157 | 1.61 | 1.16 | -1.39 |
MSN | 0.0194 | -2.68 | 4.71 | 12.57 |
ANXA3 | 0.0319 | 1.23 | -1.8 | -2.23 |
MYOM11 | 0.0335 | -1.37 | 1.58 | 2.15 |
ACADS | 0.035 | -2.01 | 1.12 | 2.24 |
GCC2 | 0.0375 | 1.04 | -3.78 | -3.92 |
FEZ2 | 0.0399 | 1.89 | -1.11 | -2.12 |
LATS2 | 0.0431 | -1.58 | -1.51 | 1.04 |
Genes with statistically significant correlation with that of Mypn in mouse hearts. KI: Knock-in Mypn mouse; KO: Knock-out Mypn mouse; WT: Wild type littermates; -: Proteins downregulated compared to WT.