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. 2017 May 2;18:338. doi: 10.1186/s12864-017-3743-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Combined gene expression and predicted activation information for the mTOR pathway in the heart and small intestine. a Gene expression and predicted activity for the mTOR pathway in the heart. b Gene expression and predicted activity for the mTOR pathway in the small intestine. Differentially expressed genes identified in our RNAseq data set are highlighted in red (upregulated) and blue (downregulated) while predicted activation states are highlighted in orange (activation) and green (inhibition). c CPA and URMA results for pathways and upstream regulatory molecules involved in mTOR signaling and other relevant growth pathways