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. 2017 Jan 23;156(2):428–437. doi: 10.1093/toxsci/kfw264

FIG. 3.

FIG. 3

Impact of TCE exposure on hepatic gene induction in dnTGFBRII mice. 8-week-old wild-type and dnTGFBRII mice were exposed to TCE (0.5 mg/ml) or vehicle (1% ethoxylated castor oil) via drinking water until 20 or 30 weeks of age. Hepatic levels of mRNAs encoding (A,B) IFNγ, (C,D) IL6, (E,F) TNFα, and (G,H) IL10 were determined by qPCR as described in Materials and Methods section. N = 4–8 mice per group for 20 weeks of age and 7–15 mice per group for 30 weeks of age. *Significantly different from wild-type mice in the same exposure group. #Significantly different from vehicle-exposed mice of the same genotype.