TABLE 1.

Detection of Plasma Anti-PDCE2 Antibodies in TCE-Exposed TGFBRII Mice

Group	Age	anti-PDCE2 Ab (% positive)
Wild-type	30 weeks	2 of 11 (18%)
Wild-type + TCE	30 weeks	4 of 11 (36%)
dnTGFBRII	30 weeks	6 of 9 (66%)
dnTGFBRII + TCE	30 weeks	7 of 7 (100%)

Eight week-old wild-type and dnTGFBRII mice were exposed to TCE (0.5 mg/ml) or vehicle (1% ethoxylated castor oil) via drinking water until 30 weeks of age. Plasma levels of anti-PDCE2 autoantibodies were determined as described in Materials and Methods section. P < .05 for genotype, but not exposure-related effects.