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Effects of QSKL on the MAPK pathway (n = 9). Western blot shows that the expressions of ERK, p-ERK, and p-JNK in the model group were upregulated compared with the sham group. QSKL could decrease levels of ERK, p-ERK/ERK, JNK, and p-JNK/JNK compared with the model group. Levels of p-ERK and JNK showed no statistical difference between the fosinopril group and the model group (∗P < 0.05, ∗∗P < 0.01, other groups versus model group).
