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Effects of QSKL on the RhoA/ROCK pathway (n = 9). Western blot shows that the expressions of RhoA, ROCK1, ROCK2, and p-MLC/MLC in the model group were upregulated compared with the sham group. QSKL could decrease the levels of RhoA, ROCK1, ROCK2, and p-MLC/MLC compared with the model group. Level of MLC showed no statistical difference between the fosinopril group and the model group (∗P < 0.05, ∗∗P < 0.01, other groups versus model group).
