Table 5.
Serum biochemistry of SD rats treated orally with Aster tataricus L. f. extracts
| Indices | Groups | |||||
|---|---|---|---|---|---|---|
| Control group | PEA group | EEA group | NEA group | REA group | AEA group | |
| Male | ||||||
| ALT (U/L) | 46.67±2.31 | 78.00±26.87* | 57.67±14.05 | 53.50±2.12 | 57.33±10.79 | 47.00±7.07 |
| AST (U/L) | 116.33±15.95 | 175.50±41.72* | 142.00±32.08 | 155.5±3.54 | 147.67±15.31 | 125.00±42.23 |
| ALP (U/L) | 155.67±13.43 | 149.50±2.12 | 150.00±19.52 | 124.00±16.97 | 143.67±29.54 | 132.50±19.09 |
| T-BIL (μmol/L) | 6.05±1.75 | 7.55±1.93 | 5.71±0.17 | 4.65±0.01 | 5.51±0.43 | 5.25±0.66 |
| TP (g/L) | 67.00±2.50 | 74.10±2.62 | 69.27±0.80 | 61.55±4.74 | 64.60±4.25 | 66.45±3.04 |
| ALB (g/L) | 34.17±2.59 | 37.30±2.26 | 35.77±0.46 | 33.15±1.91 | 34.10±1.65 | 34.35±0.21 |
| CK (U/L) | 654.67±54.00 | 1958.50±468.81** | 1745.00±87.73** | 1281.00±2.83** | 1982.33±112.22** | 1884.00±100.41** |
| LDL-C(mmol/L) | 0.26±0.04 | 0.42±0.03** | 0.28±0.03 | 0.28±0.04 | 0.25±0.06 | 0.25±0.05 |
| LDH (U/L) | 1146.67±381.34 | 1458.00±386.08 | 1179.67±310.78 | 1641.00±21.21 | 1258.00±416.45 | 1274.00±490.73 |
| Urea (mmol/L) | 6.57±1.19 | 5.95±2.33 | 6.10±0.26 | 7.50±0.14 | 7.83±2.48 | 6.50±1.84 |
| Creatinine (μmol/L) | 64.33±8.62 | 74.50±6.36 | 74.00±5.29 | 62.00±1.41 | 66.33±3.79 | 60.50±2.12 |
| HDL-C (mmol/L) | 1.07±0.15 | 1.61±0.24* | 1.10±0.05 | 1.12±0.17 | 1.19±0.22 | 1.02±0.36 |
| Glucose (mmol/L) | 5.72±0.83 | 5.29±1.53 | 4.74±0.34 | 6.10±0.56 | 5.33±0.59 | 5.37±1.02 |
| TC (mmol/L) | 1.60±0.30 | 2.30±0.28* | 1.63±0.15 | 1.60±0.28 | 1.67±0.32 | 1.70±0.14 |
| TG (mmol/L) | 1.05±0.13 | 1.15±0.07 | 1.30±0.49 | 0.75±0.07 | 1.20±0.18 | 1.21±0.07 |
| Female | ||||||
| ALT (U/L) | 45.50±4.95 | 58.67±2.52* | 45.50±2.12 | 50.33±5.51 | 45.50±3.54 | 47.33±11.01 |
| AST (U/L) | 131.40±32.74 | 141.00±30.12 | 156.50±24.75 | 152.67±43.59 | 140.00±36.77 | 116.33±23.29 |
| ALP (U/L) | 112.50±0.71 | 91.67±4.93** | 99.50±0.71 | 109.33±11.72 | 100.00±1.41 | 89.00±4.00** |
| T-BIL (μmol/L) | 4.97±1.31 | 5.48±0.92 | 7.12±0.14* | 4.96±0.66 | 7.53±0.79* | 5.19±1.06 |
| TP (g/L) | 72.24±7.50 | 71.47±4.48 | 72.65±1.77 | 67.53±1.46 | 65.65±3.75 | 72.50±1.23 |
| ALB (g/L) | 37.70±2.27 | 37.43±0.91 | 36.80±0.85 | 35.93±0.64 | 34.85±2.62 | 38.03±1.36 |
| CK (U/L) | 1544.50±286.48 | 2548.33±458.26** | 4490.50±441.94** | 3010.00±284.96** | 3084.50±665.39** | 2521.67±487.26* |
| LDL-C (mmol/L) | 0.21±0.06 | 0.27±0.04 | 0.26±0.01 | 0.24±0.05 | 0.27±0.01 | 0.27±0.07 |
| LDH (U/L) | 683.67±32.32 | 1206.67±212.59** | 1347.50±178.90** | 1265.67±197.00** | 1120.00±247.49* | 978.67±220.00 |
| Urea (mmol/L) | 7.22±0.43 | 7.20±1.57 | 6.65±0.64 | 6.93±2.14 | 7.95±1.34 | 8.10±1.84 |
| Creatinine (μmol/L) | 70.40±9.56 | 79.67±9.61 | 72.50±9.19 | 67.67±7.51 | 68.00±2.83 | 70.67±2.52 |
| HDL-C (mmol/L) | 1.81±0.22 | 1.66±0.42 | 1.72±0.05 | 1.65±0.17 | 1.77±0.54 | 2.28±0.19 |
| Glucose (mmol/L) | 5.85±1.08 | 5.07±0.80 | 4.76±0.08 | 6.09±0.55 | 5.56±1.06 | 5.08±0.57 |
| TC (mmol/L) | 2.24±0.36 | 2.20±0.46 | 2.40±0.14 | 2.10±0.20 | 2.40±0.57 | 2.83±0.31* |
| TG (mmol/L) | 0.94±0.39 | 1.13±0.22 | 1.06±0.17 | 0.76±0.14 | 0.84±0.23 | 0.59±0.11 |
Values are the mean ± SD for 6 rats in each group.
*
indicates a significant difference from controls (P < 0.05).
**
indicates a highly significant difference from controls (P < 0.01).