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. 2017 Mar 1;14(3):218–230. doi: 10.21010/ajtcam.v14i3.24

Figure 1.

Figure 1

Acute hypoglycemic effect of C. ficifolia extract (200 mg/kg equivalent to 11.6 μg of p-coumaric acid/kg) and glibenclamide (5 mg/kg) in: A) Normo-glycemic mice, *significant difference against normal control (Normal ISS); B) Alloxan-induced diabetic mice, *significant difference against diabetic control (Diabetic ISS). C) Sub-chronic hypoglycemic effect by administration during 30 days of C. ficifolia-extract (200 mg/kg/day, equivalent to 11.6 μg/kg/day of p-coumaric acid) or metformin (50 mg/kg/day) in alloxan-induced diabetic mice, *significant difference against Normal control, *significant difference against diabetic control (Alloxan ISS). Mean±S.E.M. n=5 (p<0.05).