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. 2017 Apr 1;18(4):732. doi: 10.3390/ijms18040732

Figure 7.

Figure 7

Regulation of apoptosis by lncRNA-XIST through the mopping up of miR-494 after SCI. SCI rats were randomly divided into four groups: SCI group; Lv-shRNA group; Lv-shRNA + antagomir-494 group, and sham group (n = 4 per/group). (A) Effect of antagomiR-494 on Lv-shRNA inhibition of apoptosis after SCI. (B) Effect of miR-494 knockdown on the inhibitory effect of Lv-shRNA on the expression of PTEN. (C) Effect of miR-494 knockdown in the presence of Lv-shRNA on the expression of p-AKT and p-mTOR in SCI model rats. (D) Band optical densities were measured using Image-Pro Plus software. Data are mean values ± SEM. * p < 0.05, ** p < 0.01 vs. the sham group, ## p < 0.01 vs. SCI + Lv-shRNA group.