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. 2017 Apr 5;18(4):774. doi: 10.3390/ijms18040774

Figure 2.

Figure 2

MPC and macrophage markers in pre-osteoarthritis (pre-OA) synovium. Pre-OA synovial samples from eight individuals (one patient shown as an example), were examined histologically for tissue architecture with H&E staining (A,B) and for markers of MPCs (CD90, CD271) (C–F) or macrophages (CD14, CD68) (G–J). No differences were observed in the total numbers of MPCs in the intima or subintima within the knee joints examined (K), however, decreased levels of CD14+ vs. CD68+ cells were detected in the intima and subintima. Double positive cells were also enumerated and no differences in cell number was observed in MPCs or macrophages between the subintimal vs. intimal tissue layers (L).