Skip to main content
. 2017 Apr 10;18(4):794. doi: 10.3390/ijms18040794

Figure 7.

Figure 7

GA attenuates inflammatory response in LPS-treated BALB/c mice. (A) Effects of GA on production of TNF-α, IL-6, and IL-1β in LPS-induced BALB/c mice. BALB/c mice were randomly divided into three groups. The control group was administered the same amount of solvent i.p. (n = 5). The LPS-induced group was administered LPS (250 μg/kg) (n = 6). The treatment group was administered LPS (250 μg/kg) and GA (20 mg/kg) at the same time (n = 5). Two hours after the injection, blood was harvested, and serum was separated to measure IL-6 (left), TNF-α (middle) and IL-1β (right) levels by ELISA. ### p < 0.001 versus control group; *** p < 0.05 versus LPS-treated group. (B) The effects of GA on the AMPK pathways in LPS-treated BALB/c mice. BALB/c mice were treated with the same method as in (A). Blood samples were treated with red blood cell lysis buffer to harvest immune cells for analysis of AMPK phosphorylation by Western blotting.