Table 3.
Effect of EC-12 (50 ppm) on the size distribution of intestinal polyps in Min mice.
| Dose (ppm) | Gender | Diameter (mm) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| <0.5 | 0.5 to <1.0 | 1.0 to <1.5 | 1.5 to <2.0 | 2.0 to <2.5 | 2.5 to <3.0 | 3.0 to <3.5 | 3.5 to <4.0 | 4.0 to <4.5 | ≥4.5 | ||
| 0 | Male | 13.4 ± 6.5 | 19.6 ± 7.1 | 7.0 ± 3.0 | 3.6 ± 2.9 | 2.0 ± 2.1 | 0.3 ± 0.5 | 0.3 ± 0.5 | 0.1 ± 0.4 | 0.3 ± 0.5 | 0.0 ± 0.0 |
| 50 | Male | 12.2 ± 6.1 | 21.2 ± 10.1 | 7.0 ± 6.1 | 3.1 ± 2.4 | 0.5 ± 0.7 | 0.2 ± 0.4 | 0.2 ± 0.4 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.03 ± 0.2 |
| 0 | Female | 15.8 ± 7.2 | 23.7 ± 12.4 | 6.1 ± 4.7 | 1.6 ± 0.9 | 0.9 ± 0.8 | 0.1 ± 0.3 | 0.1 ± 0.3 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| 50 | Female | 8.3 ± 4.3 * | 14.9 ± 9.1 | 5.5 ± 2.1 | 3.3 ± 3.1 | 0.9 ± 0.6 | 0.1 ± 0.4 | 0.3 ± 0.5 | 0.0 ± 0.0 | 0.1 ± 0.4 | 0.0 ± 0.0 |
Data are presented as the means ± SD. Significantly different from the untreated control group at * p < 0.05.