Table 4.
Effect of EC-12 (100 ppm) on the size distribution of intestinal polyps in Min mice.
| Dose (ppm) | Gender | Diameter (mm) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| <0.5 | 0.5 to <1.0 | 1.0 to <1.5 | 1.5 to <2.0 | 2.0 to <2.5 | 2.5 to <3.0 | 3.0 to <3.5 | 3.5 to <4.0 | 4.0 to <4.5 | ≥4.5 | ||
| 0 | Male | 7.2 ± 4.4 | 16.6 ± 2.8 | 8.1 ± 3.6 | 4.3 ± 1.8 | 2.1 ± 0.8 | 0.8 ± 0.8 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.3 |
| 100 | Male | 3.9 ± 4.2 | 12.9 ± 4.5 | 10.4 ± 4.9 | 4.6 ± 2.0 | 1.4 ± 1.0 | 0.1 ± 0.3 | 0.2 ± 0.4 | 0.1 ± 0.3 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| 0 | Female | 9.9 ± 4.3 | 20.9 ± 7.2 | 6.1 ± 3.0 | 2.5 ± 1.1 | 1.8 ± 1.4 | 0.6 ± 0.7 | 0.3 ± 0.5 | 0.0 ± 0.0 | 0.3 ± 0.5 | 0.0 ± 0.0 |
| 100 | Female | 3.9 ± 3.6 * | 12.5 ± 7.6 * | 7.9 ± 5.1 | 3.9 ± 2.0 | 1.1 ± 1.0 | 0.4 ± 0.5 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.4 | 0.0 ± 0.0 |
Data are presented as the means ± SD. Significantly different from the untreated control group at * p < 0.05.