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. 2017 Apr 18;18(4):857. doi: 10.3390/ijms18040857

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Clinical features of the patients. (A,B) Magnetic resonance imaging (MRI) showed a mildly enlarged bilateral ventricle in Case 1; (C,D) A mildly enlarged left ventricle was found in Case 2 by MRI; (E,F) Several parts of the brain (cerebellum, frontoparietal, basal ganglia, and thalamus) in Case 4 had symmetrical patchy abnormal signals; (G) Magnetic resonance spectroscopy (MRS) revealed the brain of Case 4 had an abnormal increased lactate peak and reduced N-acetyl aspartate (NAA) peak, which is marked by the red and green arrows, respectively; (H) The facial picture of Case 4 with a strabismic right eye.