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In vitro function studies of Asp119Asn and 704delC in COS-7 cell line. (A) The Western blotting results showed 704delC leads to a lower protein expression level as well as a slightly smaller protein size, Asp119Asn has no effect on the protein expression; (B) The FBPase activity of Asp119Asn and 704delC markedly decreased compared with that of the wild-type. The data represent mean values of FBPase activities performed three times. **: p value < 0.01
