Table 1.
Genes differentially expressed in the skeletal muscle of finishing pigs fed a lysine-deficient vs. a lysine-adequate diet.
| Gene Symbol | Gene Description | GenBank 1 | p-Value 2 |
|---|---|---|---|
| Down-regulated genes | |||
| CPEB2 | Cytoplasmic polyadenylation element binding protein 2 | NM_001185049 | <0.001 |
| CST9L | Cystatin 9-like | XM_003134304 | 0.007 |
| ERLEC1 | Endoplasmic reticulum lectin 1 | XM_003125147 | 0.011 |
| ESYT1 | Extended synaptotagmin-like protein 1 | XM_003126262 | 0.009 |
| HOXA11B | Homeobox A11 | AF453292 | 0.001 |
| LCLAT1 | Lysocardiolipin acyltransferase 1 | NM_001142845 | 0.032 |
| MYL6 | Myosin, light chain 6 | NM_001163997 | 0.011 |
| RASSF7 | Ras association domain family member 7 | XM_003122393 | 0.004 |
| UBTD1 | Ubiquitin domain containing 1 | XM_003359315 | 0.003 |
| ZMAT5 | Zinc finger, matrin-type 5 | XM_001929010 | 0.035 |
| ZNF181 | Zinc finger protein 181 | NM_001244818 | 0.005 |
| Up-regulated genes | |||
| AMD1 | Adenosylmethionine decarboxylase 1 | XM_003121345 | 0.014 |
| ATP6V1G2 | Atpase, H+ transporting, lysosomal 13 kDa, V1 subunit G2 | NM_001145380 | 0.002 |
| C7H6orf136 | Chromosome 6 open reading frame 136 | NM_001243459 | 0.003 |
| CCDC25 | Coiled-coil domain containing 25 | NM_001243572 | 0.023 |
| CD164 | CD164 molecule | XM_001924626 | 0.022 |
| CHIT1 | Chitinase 1 | XM_003130296 | 0.005 |
| CHORDC1 | Cysteine and histidine-rich domain (CHORD) containing 1 | NM_001113446 | 0.010 |
| CHSY3 | Chondroitin sulfate synthase 3 | XM_003123906 | 0.049 |
| CIDEC | Cell death-inducing DFFA-like effector c | NM_001112689 | 0.024 |
| DNAJA1 | Dnaj (Hsp40) homolog, subfamily A, member 1 | NM_001244163 | 0.003 |
| eIF2S2 | Eukaryotic translation initiation factor 2 subunit 2 | XM_005672861 | 0.002 |
| FUT1 | Fucosyltransferase 1 | NM_214068 | 0.003 |
| GABPB1 | GA binding protein transcription factor, β subunit 1 | XM_005659610 | 0.002 |
| GPR182 | G protein-coupled receptor 182 | XM_003126290 | 0.000 |
| H1FOO | Oocyte-specific H1 histone | NM_001205063 | 0.016 |
| HOXA4 | Homeobox A4 | XM_003134841 | 0.037 |
| HSP90AB1 | Heat shock protein 90 kDa α (cytosolic), class B member 1 | NM_001244433 | 0.007 |
| LGALS13 | Lectin, galactoside-binding, soluble, 13 | NM_001142841 | 0.003 |
| ME1 | Malic enzyme 1, NADP+-dependent, cytosolic | XM_001924333 | 0.050 |
| MIR3187 | MicroRNA 3187 | NR_036154 | 0.002 |
| PHGDH | Phosphoglycerate dehydrogenase | NM_001123162 | 0.000 |
| PSPH | Phosphoserine phosphatase | NM_001243221 | 0.009 |
| RND3 | Rho family GTPase 3 | NM_214296 | 0.003 |
| SCD | Stearoyl-CoA desaturase (δ-9-desaturase) | NM_213781 | 0.023 |
| SERP1 | Stress-associated endoplasmic reticulum protein 1 | NM_001243260 | 0.039 |
| TXNL1 | Thioredoxin-like 1 | NM_001244276 | 0.030 |
| UBE2B | Ubiquitin-conjugating enzyme E2B | NM_001257356 | 0.011 |
| ZIC1 | Zic family member 1 | XM_003358599 | 0.011 |
1 The accession number of the gene sequence resided in the GenBank database (http://www.ncbi.nlm.nih.gov); and 2 p-Value was obtained from the orthogonal contrast analysis using the Partek Genomics Suite software (Partek Inc., St. Louis, MO, USA). A change in gene mRNA abundance was considered significant when the p-value was less than or equal to 0.05.