Table 1. Characteristics of the Included Patients.
| Characteristics | CD patients (n = 106) |
|---|---|
| Male, n (%) | 72 (67.9) |
| Active smoker, n (%) | 3 (2.8) |
| Age (years) at diagnosis, mean (SD) | 26.6 (9.5) |
| Montreal classification | |
| Age (years) at diagnosis, n (%) | |
| ≤ 16 years (A1) | 10 (9.4) |
| 17 - 40 years (A2) | 83 (78.3) |
| > 40 years (A3) | 13 (12.3) |
| Disease site, n (%) | |
| Ileum (L1) | 36 (34.0) |
| Colon (L2) | 7 (6.6) |
| Ileocolon (L3) | 63 (59.4) |
| Disease behavior, n (%) | |
| Inflammatory (B1) | 55 (51.9) |
| Stricturing (B2) | 41 (38.7) |
| Penetrating (B3) | 10 (9.4) |
| Perianal disease, n (%) | 28 (26.4) |
| Extraintestinal manifestations, n (%) | 10 (9.4) |
| Disease duration (m), n (%) | |
| ≤ 18 | 84 (79.2) |
| > 18 | 22 (20.8) |
| Gastrointestinal surgery before infusion, n (%) | 27 (25.5) |
| Therapeutic regimen, n (%) | |
| Step-up | 30 (28.3) |
| Top-down | 76 (71.7) |
| CRP level at week 0/30, median (IQR) | 9.9 (3.0 - 38.9)/1.49 (0.48 - 6.11) |
| Alb level at week 0/30, median (IQR) | 37.7 (33.7 - 41.6)/42.3 (39.2 - 45.7) |
| WBC level at week 0/30, median (IQR) | 7.12 (5.91 - 8.92)/5.57 (4.83 - 6.58) |
| Hb level at week 0/30, median (IQR) | 115.0 (101.0 - 130.3)/129.0 (117.5 - 143.0) |
| Hct level at week 0/30, median (IQR) | 36.6 (32.7 - 40.5)/39.3 (35.9 - 43.2) |
| CDAI at week 0/30, median (IQR) | 213.5 (160.0 - 265.3)/64.5 (39.8 - 90.5) |
| AZA at IFX discontinuation, n (%) | 77 (72.6) |
CRP: C-reactive protein; Alb: albumin; WBC: white blood cell; Hb: hemoglobin; Hct: hematocrit; AZA: azathioprine; CDAI: Crohn’s disease activity index; SD: standard deviation; IQR: interquartile range.