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. 2017 May 1;216(5):1473–1488. doi: 10.1083/jcb.201510042

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© 2017 Longmate et al.

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Figure 1. — α9β1 inhibits α3β1-dependent secretion of keratinocyte factors that induce endothelial cell migration. Transwell assays were performed to compare migration of HUVECs in response to conditioned medium from MK cells that expressed α3β1 and/or α9β1 in various combinations, as indicated. Graph shows HUVEC migration as a fold increase over that in cells treated with unconditioned medium as a baseline (set to 1.0). Means ± SEM are shown. n = 3 independent experiments. A one-way analysis of variance with Newman-Keuls’s multiple comparisons test was used. *, P < 0.05 compared with nonasterisked groups.