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. 2016 Oct 26;20(1):22–30. doi: 10.1093/ijnp/pyw087

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© The Author 2016. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Response and remission rates for Montgomery-Åsberg Depression Rating Scale (MADRS) and response rates for Clinical Global Impression-Improvement (CGI-I). (A) Percentage of patients with MADRS response, defined as a ≥50% reduction from baseline in total score. (B) Percentage of patients with MADRS remission, defined as a total score decrease ≥50% from baseline and ≤10. (C) CGI-I response rates, defined as a score of 1 (very much improved) or 2 (much improved). All patients received ADT+brexpiprazole 1–3 mg/d switched from previous adjunctive or combination treatment; primary antidepressant treatment (ADT) kept constant. Analyzed by exact binomial 95% CI on observed cases (OC) data.