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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Circ Cardiovasc Qual Outcomes. 2017 Apr;10(4):e003418. doi: 10.1161/CIRCOUTCOMES.116.003418

Table 2.

Gender specific outcomes in propensity matched samples reported as rates/ 100 patient year of follow-up (95% CI) and (number of events)

Males Females
Dabigatran 150 mg twice daily Rivaroxaban 20 mg once daily Warfarin Dabigatran 150 mg twice daily Rivaroxaban 20 mg once daily Warfarin
Number of patients 7,618 7,618 7,618 11,031 11,031 11,031
Stroke 1.53 (1.31 – 1.81)(69) 0.97 (0.66 – 1.24)(48) 1.42 (1.29 – 1.77)(68) 1.44 (1.21 – 2.01) (107) 1.67 (1.20 – 2.11) (119) 1.75 (1.41 – 2.59) (130)
Any hemorrhage 3.16 (2.61 – 3.69)(142) 3.86 (3.66 – 4.48)(189) 4.23 (3.81 – 4.78) (202) 3.82 (3.10 – 4.27) (282) 5.18 (4.70 – 5.99) (327) 3.90 (3.01 – 4.36) (288)
GI hemorrhage (GIH) 2.73 (2.15 – 3.27) (123) 3.30 (3.09 – 4.01) (162) 3.24 (2.83 – 3.82) (155) 3.49 (2.88 – 3.89) (258) 4.55 (3.98 – 5.24) (288) 2.89 (2.13 – 3.61) (214)
Intra-cranial Hemorrhage (ICH) 0.13 (0.03 – (0.29)(6) 0.26 (0.08 – 0.58) (13) 0.44 (0.33 – 0.91) (21) 0.21 (0.01 – 0.33) (16) 0.38 (0.10 – 0.96) (24) 0.54 (0.37 – 1.01) (40)
Other Non-GI hemorrhage 0.49 (0.10 – 0.77) (22) 0.55 (0.15 – 0.83) (27) 1.02 (0.87 – 1.67) (49) 0.35 (0.06 – 0.51) (26) 0.66 (0.53 – 0.81) (42) 1.07 (0.90 – 1.77) (80)