Table 4.
Effects of T and VitE on ATZ-induced cellular apoptosis
| Control-sham | ATZ-induced | ATZ+VitE | ATZ+T | ATZ+VitE+T | |
|---|---|---|---|---|---|
| Total Sertoli cells | 41.33 ± 1.52a | 22.64 ± 1.22b | 35.00 ± 2.01c | 40.37 ± 2.11a,d | 40.70 ± 2.56d |
| Apoptotic Sertoli cells | 1.38 ± 0.42a | 17.25 ± 0.95b | 13.00 ± 2.16c | 12.75 ± 0.95c | 7.25 ± 1.70d |
| TSE/TASE (%) | 3.39 | 76.1 | 34.1 | 31.58 | 17.81 |
| Total Leydig cells | 35.33 ± 2.08a | 18.33 ± 1.52b | 30.64 ± 2.08c | 29.66 ± 1.52c | 35.58 ± 1.43d |
| Apoptotic Leydig cells | 0.90 ± 0.27a | 10.75 ± 0.95b | 8.25 ± 0.50c | 8.86 ± 0.27c | 5.03 ± 0.76d |
| TL/TAL (%) | 2.5 | 58.6 | 26.6 | 27.81 | 15.4 |
| Total spermatogonia cells | 51.75 ± 4.99a | 33.75 ± 2.62b | 40.82 ± 1.96c | 38.25 ± 1.06c | 45.50 ± 2.64d |
| Apoptotic spermatogonia cells | 2.00 ± 1.41a | 26.25 ± 1.70b | 18.75 ± 0.95c | 21.00 ± 2.00c | 12.14 ± 1.82d |
| TS/TAS (%) | 3.8 | 77.7 | 46.01 | 54.9 | 26.68 |
All data are presented in mean ± SD and %.
a vs. b; Significant at P<0.05, c, d vs. b; Significant at P<0.05, ATZ; Atrazine, VitE; Vitamin E, T; Testosterone, TSE; Total Sertoli cells, TASE; Total apoptotic Sertoli cells, TL; Total Leydig cells, TAL; Total apoptotic Leydig cells, TS; Total spermatogonia cells, and TAS; Total apoptotic spermatogonia cells.