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. 2017 Mar 27;9(5):571–588. doi: 10.15252/emmm.201606987

Figure EV1. Effect of niacin on PG, RvE1, and LXA4 production in mice after DSS challenge.

Figure EV1

  1. Mass spectrometry analysis of PG production in colons from niacin (600 mg/kg)‐treated mice after DSS challenge. Vehicle, n = 6; niacin 600 mg/kg, n = 7.
  2. Measurement of urinary metabolite of PGs in niacin (600 mg/kg)‐treated mice. PGEM, 11α‐hydroxy‐9,15‐dioxo‐2,3,4,5‐tetranor‐prostane‐1,20‐dioic acid; PGIM, 2,3‐dinor‐6‐keto‐PGF1α; TxM, 2,3‐dinor‐TxB2; PGFM, 13,14‐dihydro‐15‐keto‐PGF2α. n = 6.
  3. Mass spectrometry analysis of RvE1 and LXA4 production in colons from niacin (600 mg/kg)‐treated mice after DSS challenge. n = 6.
Data information: Data are shown as mean ± SEM. Data are representative of at least two independent experiments. Statistical significance was determined using unpaired Student's t‐tests. (A) ## P < 0.01. (B) # P < 0.05, ## P < 0.01.