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. 2017 Mar 27;9(5):571–588. doi: 10.15252/emmm.201606987

Figure 8. The therapeutic effect of niacin retention enema on patients with moderately active UC.

Figure 8

  1. Clinical study design of niacin retention enema therapy. MDS: metronidazole, dexamethasone, starch.
  2. Effect of niacin retention enema on urinary tetranor PGDM production in patients.
  3. Representative endoscopic images of colon mucosa from patients involved in this study. Superficial ulceration, granulocyte infiltration, and distorted/branching crypts are apparent in biopsies from patients with active disease, whereas those from the healthy subjects or those in remission appear normal.
  4. Changes of Mayo score of UC patients before and after niacin retention enema therapy.
  5. Representative H&E staining colon mucosa from UC patients. Scale bar: 100 μm.
Data information: P‐values were calculated using paired Student's t‐test. (B) *P < 0.05 as indicated, n = 8. (D) **P < 0.01 as indicated, n = 26.