Skip to main content
. 2017 Apr 4;9(5):589–604. doi: 10.15252/emmm.201607027

Figure EV4. RIG‐I expression in non‐haematopoietic cells is not required for IL‐23‐induced psoriasis‐like skin inflammation.

Figure EV4

  • A
    Lethally irradiated WT and RIG‐I−/− mice were adoptively transferred with WT bone marrow (BM) cells, and the generated chimeric mice were subjected to IL‐23‐induced psoriasis‐like skin inflammation. Data are presented on the indicated day relative to day 0. Significant differences are indicated: one‐way ANOVA, n = 5 per group (mean ± SEM).
  • B
    Representative H&E staining and Ki67 immunostaining of the ears treated as in (A), n = 5 per group. Scale bar: 50 μm.
  • C, D
    Acanthosis (C) and dermal cellular infiltrates (D) of WT BM‐WT or WT BM‐RIG‐I−/− mice treated with IL‐23. Significant differences are indicated: two‐tailed Student's t‐test, n = 5 per group (mean ± SEM).