. 2016 Jun 22;52(3):325–333. doi: 10.1111/jre.12395

Table 2.

Comparison of cytokine concentrations detected in cell‐culture supernatants

A: cytokines assessed at 4‐h culture time point	smbflive	smbfdead	smbfdead	mix live
A: cytokines assessed at 4‐h culture time point	mix live	mix live	mix dead	mix dead
IL‐8	00.078	0.174	0.404	0.118
IL‐1β	0.001	0.001 ^*	0.036 ^*	0.968
IL‐6	0.071	0.014	0.069	0.216
GM‐CSF	0.033	0.033	0.500	0.359
G‐CSF	0.002 ^*	0.004	0.094	0.034 ^*
TNF	1.000	1.000	1.000	1.000

B: cytokines assessed at 24‐h culture time point	smbflive	smbflive	smbfdead	smbfdead	pgbflive	pgbflive	pgbfdead	pgbfdead	mix live
B: cytokines assessed at 24‐h culture time point	pgbfdead	mix live	mix live	mix dead	pgbfdead	mix live	mix live	mix dead	mix dead
IL‐8	0.162	0.055	0.202	0.772	0.010	0.001 ^*	0.022	0.030	0.004
IL‐1β	0.348	0.083	0.002 ^*	0.025	0.663	0.337	0.199	0.430	0.007
IL‐6	0.400	0.231	0.020	0.198	0.598	0.368	0.020	0.241	0.001 ^*
GM‐CSF	0.009	0.000 ^*	0.015	0.423	0.357	0.241	0.026	0.009	0.000 ^*
G‐CSF	0.087	0.013	0.020	0.205	0.532	0.299	0.085	0.077	0.017
TNF	1.000	0.423	0.423	1.000	1.000	0.423	1.000	1.000	0.423

G‐CSF, granulocyte colony‐stimulating factor; GM‐CSF, granulocyte–macrophage colony‐stimulating factor; IL‐1α, interleukin‐1alpha; IL‐1β, interleukin‐1beta; IL‐8, interleukin‐8; TNF, tumour necrosis factor.

Values calculated using Welch's t‐test are shown in italics. Bold denotes statistically significant differences in the comparison listed at top.

bf, biofilm; dead, fixed; mix, mixed species; pg, Porphyromonas gingivalis; sm, Streptococcus mitis. Comparisons that showed no differences were omitted from the table.

*Significant after Bonferroni correction.