Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Feb 3;2(1):120–130. doi: 10.1002/btm2.10052

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors. Bioengineering & Translational Medicine is published by Wiley Periodicals, Inc. on behalf of The American Institute of Chemical Engineers

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Coat activity was confirmed by in vitro assays specific for each adjuvant. (a) OVA‐FliC nanoparticles and OVA‐OVA nanoparticles with soluble FliC (sFliC) admixed demonstrated similar levels of TLR‐5‐dependent NFκB activation in Hela cells as compared to OVA‐OVA nanoparticles. Each bar is an average of two technical replicates (n = 2). (b) Complement activation as determined by anti‐TCC ELISA after mixing nanoparticles with human serum. IgM‐coated OVA nanoparticles and uncoated OVA nanoparticles demonstrated similar levels of complement activation. Each average is composed of two technical replicates in each of two serum samples (n = 4)