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. 2017 Feb 3;2(1):120–130. doi: 10.1002/btm2.10052

Table 2.

Summary of immune responses to different adjuvants on OVA nanoparticles

Nanoparticle type IgG1 IgG2a IFN‐γ IL‐4 CD44+/CD62L+ T cells Affinity maturation
OVA‐OVA Low Low No No No Yes
OVA‐FliC High High No No No Yes
OVA‐IgM High High Yes No Yes No
OVA + soluble FliC High High No Yes No No
OVA‐FliC + OVA‐IgM High High Yes Yes No No

Note. T cell responses of “Yes” and “No” have been made with respect to the PBS (G6) control. Flic = flagellin; IgM = immunoglobulin M; IgG = immunoglobulin G; OVA = ovalbumin; IFN‐γ = interferon γ; IL‐4 = interleukin 4.