Fig 5. Polyfunctional responses of CD8⁺ T cells after stimulation with an HIV Gag peptide pool.

A: Two prevalent polyfunctional subsets (CD107a⁺MIP1β⁺IFN-γ⁺ and CD107a⁺MIP1β⁺) increased after four months of etoricoxib in ART-naïve patients. ART and COX-2i use indicated, coloured bar pairs represent response at baseline and four months, respectively. B: The CD8⁺ T cell response tended to be more polyfunctional after four months of etoricoxib in ART-naïve patients (2 leftmost pies). P-values derived from unpaired permutation tests.